Careers

Postdoctoral Scientist in Molecular Antibody Engineering

Galileo Biotech is a subsidiary of Antharis Therapeutics LLC, USA, a multinational biopharmaceutical company developing new treatments for a variety of unmet medical needs, particularly various types of cancer. Our company leverages cutting-edge science and our proprietary platform to develop therapeutic monoclonal antibodies with the ultimate goal of providing treatments for devastating diseases.

Essential Job Functions

• General molecular biology techniques, including subcloning of variable chains into human IgG expression vectors to generate chimeric antibodies using Gibson Assembly.

• Isolate variable domains to drive antibody discovery from hybridoma but cloned sources, using PCR methodologies.

• Express large amounts of chimeric antibodies through large-scale transient transfection in expiCHO cells.

• Purify large-scale chimeric antibodies using affinity chromatography.

• Humanize mouse antibodies using complementarity-determining region (CDR) grafting technology and computer-assisted molecular modeling.

• Develop processes and assays to discover, generate, and characterize antibodies against selected target antigens.

• Contribute to target antigen discovery and development programs.

Position Requirements

On-site | Full-time | Senior | Associate Postdoctoral Researcher

• Postdoctoral degree in Molecular Biology, Immunology, Biochemistry, or related fields with 2-3 years of experience.

• Strong hands-on experience in molecular biology is required.

• Proven success in mouse antibody humanization is essential.

• Experience in applying deep sequencing/barcoding in variable chain sequencing is a plus.

• Experience in guiding, training, and managing others is desired.

Job Location

Rio de Janeiro, RJ

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